As a NAS sure if you point one of your VM's to the IP of the NAS and run it as a Samba/SMB share.
If you are looking to use the DNS-325 as a low level block level I/O storage for your VM's then no. You will need at least a SAN or NAS that uses ISCSI and from experience recommend that the datasheet mentions compatibility with the version of Hyper-V/Citrix/VSphere etc that you intend to use it. Preferrably "certified".