I would lean more towards the adapter settings or drivers on your wireless NIC. What kind does it have? Also, please re-explain the issue? So you have two laptops, one wired and one wireless? And the problem seems to happen while gaming on the wireless laptop while doing some type of heavy use on the wired laptop?
Come to think of it, if the issue was random disco which were resolved by turning off the auto scan, which then lead to lag spikes, your probably getting random interference on your wireless connection. Before it was enough to make the router jump to another wireless channel, and it wasn't communicating that change correctly with the laptop sometimes. And now that you turned it off, that same interference that used to cause the channel to changes, causes the lag spike. But thats speculation.