What wireless modes are you using? Under Setup/Wireless/Manual.
Try single mode G or mixed G and N on 2.4Ghz and single mode N on 5Ghz?
What security mode are you using? Preferred security is WPA-Personal. WPA2/Auto AES only. Some WiFi adapters don't support AES, so you might want to try TPIK only.
Any cordless house phones?
Any other WiFi routers in the area? Use InSSIDer to find out. Need to see if you have any near by WiFi routers.
Turn off Short GI and Extra Wireless Protection if you have it. Under Advanced/Advanced Wireless.
Turn off all anti virus and firewall programs on PC while testing. 3rd party firewalls are not generally needed when using routers as they are effective on blocking malicious inbound traffic.
Turn off all devices accept for one wired PC while testing.
Maybe someone can review your router settings with you using
teamviewer if your interested. Its safe and secure.