Without getting into "If you really need a high level of security, why did you buy this particular NAS?" ...
The best way to secure the 323 is by use of Users & Passwords. That is as complex as security gets on this device. If you use the default config once you have drives installed, everything is accessable to anyone. For the majority of home consumers, this is all they want and don't care.
If you want to take it to the next level, you can go to Network Access, specify some users & groups, delete the existing share, and create new share(s) with the user/group security. As with all User-based password security, your vulnerability is going to be social networking "Oh, yeah, my password is ..." or a weak, guessable password.
Should you need more than that, you'll need to look into fun_plug and have a strong Linux background or consider more secure storage environments such as a Windows domain.