It is not about timeout. It seems that connection is lost for a second or so. It happens randomly, but probability increases with time.
The funny thing is, that connection repairs almost instantly so for example backup program is able to copy next file and only one or two file is lost during 50GB backup.
Unfortunately such a connection lost is a killer for a large file transfer.
Of course we are taling about CIFS.
If you have a time try using NFS or FTP and see, if there are connection lost with these protocols, apart from FTP being much slower than CIFS.