No - you do not.
Depending on the equipment involved you should see an increase of 10~50% in throughput when using jumboframe.
What I had previously outlined was what happens when you are transferring data between endpoints where one supported jumboframe and the other does not, there will be no benefit to using jumboframe there, because it's not supported.
If you have equipment that supports jumboframe, enable jumboframe and do your own tests, all you have to lose is your time.